Title : Nanoengineered Optoelectronic Neurointerfaces
Speaker: Sedat Nizamoglu, Department of Electrical and Electronics Engineering, Koç University.
Date : February 2nd, 2021, Tuesday
Time : 15.30
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Meeting ID: 729 064 5404
Colloidal quantum dots (QDs) offer attractive electronic, optical and surface properties.1 Although the synthesis, electronic structure and optoelectronic applications of quantum dots have been widely explored, little attention has been paid to their potential for neural interfaces.
In this talk, I will discuss quantum dot incorporated light-activated neural interfaces that can effectively and safely control neural activity in device architectures.2 I will describe the neuromodulators starting from nanomaterial synthesis upto their in-vitro application.3 I will explain our recent findings on the control of Faradaic and capacitive (non-Faradaic) charge transfer mechanisms at
nanobiojunctions.4-5 I will demonstrate that the control of charge- and exciton-transfer at nanoscale can led to the photostimulation of neurons at low light intensity levels.6-9 These findings open-up new approaches towards safe, non-genetic and all-optical control of neural activity.10
- Kotov, N. A.; Winter, J. O.; Clements, I. P.; Jan, E.; Timko, B. P.;
Campidelli, S.; Pathak, S.; Mazzatenta, A.; Lieber, C. M.; Prato, M., Nanomaterials for neural interfaces. Advanced Materials 2009, 21 (40), 3970-4004.
- Bahmani Jalali, H.; Mohammadi Aria, M.; Dikbas, U. M.; Sadeghi, S.;
Ganesh Kumar, B.; Sahin, M.; Kavakli, I. H.; Ow-Yang, C. W.; Nizamoglu, S., Effective neural photostimulation using indium-Based type-II quantum dots. ACS nano 2018, 12 (8), 8104-8114.
- Bahmani Jalali, H.; Sadeghi, S.; Sahin, M.; Ozturk, H.; Ow-Yang, C.
W.; Nizamoğlu, S., Colloidal Aluminum Antimonide Quantum Dots. Chemistry of Materials 2019.
- Aria, M. M.; Srivastava, S. B.; Sekerdag, E.; Dikbas, U. M.; Sadeghi,
S.; Pering, S. R.; Cameron, P. J.; Gursoy‐Ozdemir, Y.; Kavakli, I. H.; Nizamoglu, S., Perovskite‐Based Optoelectronic Biointerfaces for Non‐Bias‐Assisted Photostimulation of Cells. Advanced Materials Interfaces 2019, 1900758.
- Han, M.; Srivastava, S. B.; Yildiz, E.; Melikov, R.; Surme, S.;
Dogru-Yuksel, I. B.; Kavakli, I. H.; Sahin, A.; Nizamoglu, S., Organic Photovoltaic Pseudocapacitors for Neurostimulation. ACS applied materials & interfaces 2020, 12 (38), 42997-43008.
- Srivastava, S. B.; Melikov, R.; Aria, M. M.; Dikbas, U. M.; Kavakali,
- H.; Nizamoglu, S., Band Alignment Engineers Faradaic and Capacitive Photostimulation of Neurons Without Surface Modification. Physical Review Applied 2019, 11 (4), 044012.
- Bahmani Jalali, H.; Karatum, O.; Melikov, R.; Dikbas, U. M.; Sadeghi,
S.; Yildiz, E.; Dogru, I. B.; Ozgun Eren, G.; Ergun, C.; Sahin, A., Biocompatible Quantum Funnels for Neural Photostimulation. Nano letters 2019, 19 (9), 5975-5981.
- Srivastava, S. B.; Melikov, R.; Yildiz, E.; Dikbas, U. M.; Sadeghi,
S.; Kavakli, I. H.; Sahin, A.; Nizamoglu, S., Bulk-heterojunction photocapacitors with high open-circuit voltage for low light intensity photostimulation of neurons. Journal of Materials Chemistry C 2021.
- Srivastava, S. B.; Melikov, R.; Yildiz, E.; Han, M.; Sahin, A.;
Nizamoglu, S., Efficient photocapacitors via ternary hybrid photovoltaic optimization for photostimulation of neurons. Biomedical Optics Express 2020, 11 (9), 5237-5248.
- Melikov, R.; Srivastava, S. B.; Karatum, O.; Dogru-Yuksel, I. B.;
Dikbas, U. M.; Kavakli, I. H.; Nizamoglu, S., Bidirectional optical neuromodulation using capacitive charge-transfer. Biomedical Optics Express 2020, 11 (11), 6068-6077.
Sedat Nizamoglu is an associate professor in the department of Electrical and Electronics Engineering and the director of IDEALAB (Innovative Devices and Interfaces Laboratory) at Koc University, Istanbul, supported by ERC (European Research Council). Immediately after receiving his PhD degree at Bilkent University in 2011, he continued as a Bullock-Wellman Fellow with a joint affiliation with Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital in USA. His research focuses on the demonstration of innovative bioelectronic and optoelectronic devices and interfaces for the applications to energy, medicine, and environment. He has published more than 70 research papers in prestigious journals including Nature Communications, Nature Photonics, Advanced Materials and Nano Letters. He received numerous awards such as IEEE Research Encouragement Award (Turkey), Encouragement Award by TUBITAK (Turkish NRF), Outstanding Young Scientist Award by Turkish Academy of Sciences and Science Academy, Innovation Award by European Technology Platform for Photonics and SPIE Scholarship Award in Optical Science and Engineering. He was also recognized by MIT Technology Review as Innovator Under 35 Turkey.